产品货号：
Z25021
中文名称：
RASGAP/RASA1抗体
英文名称：
Anti-RASGAP/RASA1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-RASGAP/RASA1 Antibody |
| 指标别名 | CM AVM;CMAVM;GAP;GTPase activating protein;p120GAP;p120RASGAP;PKWS;Ras p21 protein activator;RASA;RASA1;RASGAP |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,ICC/IF,FCM |
| 基因名称 | RASA1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human RASA1 (1018-1047aa AQQHVLKKLLAITELLQQKQNQYTKTNDVR),different from the related rat sequence by one amino acid. |
| 实际分子量 | 100KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | RASA1,also known as RAS p21 protein activator 1,is a 120-kDacytosolic human protein.The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins.The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart.Acting as a suppressor of RAS function,the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS,thereby allowing control of cellular proliferation and differentiation.Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas.Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous malformations (AVM) and Parkes Weber syndrome.Alternative splicing results in two isoforms where the shorter isoform,lacking the N-terminal hydrophobic region but retaining the same activity,appears to be abundantly expressed in placental but not adult tissues. |
| Uniprot ID | P20936 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | RAS p21 protein activator (GTPase activating protein) 1 |
| 蛋白名全称 | Ras GTPase-activating protein 1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells |
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